Sunday, January 31, 2021

Israeli Breakthrough: Researchers Discover New Target to Kill Cancer Cells

Cancer treatment

Tel Aviv University researchers discovered a novel approach to target cancer cells. 

By Yakir Benzion, United With Israel

Researchers from Tel Aviv University (TAU) have discovered that the abnormal number of chromosomes in cancerous cells could prove to be the “Achilles heel” of the disease, paving the way for future drugs to attack the new-found weak spot.

While researchers have known for decades about the abnormal number of chromosomes of cancer cells, a unique characteristic known as “aneuploidy,” their understanding of how aneuploidy contributes to the development and spread of cancer has been limited.

TAU researchers discovered the critical point at which cancerous aneuploid cancer cells are sensitive to damage (the mitotic checkpoint) and the reason for heightened sensitivity in this location.

Drugs that target this mechanism could represent major breakthroughs in personalized cancer medicine.

The results of the TAU-led study suggest that it will be possible to use aneuploidy as a biological marker to identify patients who would respond better to specific drugs.

The study at TAU’s Sackler Faculty of Medicine was done in collaboration with six other laboratories in four other countries and was published last week in the prestigious peer-reviewed journal Nature.

According to Dr. Uri Ben-David, aneuploidy is the most common genetic change in cancer. Approximately 90% of solid tumors, such as breast cancer and colon cancer, and 75% of blood cancers are aneuploid in nature.

“It should be emphasized that the study was done on cells in a culture and not on cancer patients,” said Dr. Ben-David. “In order to translate it to treatment of cancer patients, many more follow-up studies must be performed. Still, even at this stage it is clear that the study could have a number of medical implications.”

Israeli Start Up Initiative Attracts Entrepreneurs from Syria, Libya, Iraq, and Gaza

High tech.

The group includes people from Syria, Iraq, Saudi Arabia, Libya, Tunisia, Egypt, Morocco, Jordan, and the Gaza Strip, who promote high-tech projects and receive training and practical tools.

By TPS

A group of young entrepreneurs from Arab countries is participating in weekly zoom meetings as part of a unique Israeli program for the development of startups and social initiatives.

The group includes young men and women from Syria, Iraq, Saudi Arabia, Libya, Tunisia, Egypt, Morocco, Jordan, the Gaza Strip, and the Palestinian Authority (PA), who promote high-tech projects and receive training and practical tools on how to realize their dreams in meetings hosted by leading figures in the Israeli innovation industry.

This multicultural program is the first of its kind and aims to make the entrance to the ecosystem of the Israeli startup nation accessible.

Among the projects promoted under the program is an organization that connects children from different ethnic backgrounds through joint actions to encourage social diversity and a site establishing a regional nature museum and other initiatives.

The training is shared by Israelis and people from the PA.

Some 40% of the program participants are women.

The program encompasses all stages of the development of new ventures, including market research, construction of a plan and business model, development and connection to an array of potential partners and investors in Israel and around the world.

The unique Starting Up Together program is a collaboration between the Peres Center for Peace and Innovation, the Ebay Israel Development Center, and the Center for Smart Cities at Bar Ilan University and funded by the Edmond de Rothschild Israel Foundation.

Opinion: Long-Term Impact of the Abraham Accords in Africa

Israel Africa

In every field, from dairy production to satellite technology, Israel can help Africa to leapfrog over its deficiencies in infrastructure and make up for its lack of development.

By Ben Levitas, Lay of the Land

Although relations with Africa were low on Trump’s agenda, he set in motion some momentous foreign relations events that will have enduring consequences that offer the Biden administration some tantalizing opportunities to expand American influence in Africa. While Trump spoke of “pivoting out” of the region, it is likely that Biden will deploy more resources to Africa, both to counter China’s growing influence and because of the opportunities that Africa offers.

The historic events that overturned 72 years of hostility are the establishment of diplomatic relations between several Muslim majority countries and Israel. Known by the epithet as the “Abraham Accords”, which recognized the historic and cultural bonds shared by the Arabs and Jews, Trump managed to sweep aside decades of animosity and boycotts to inaugurate mutual recognition and diplomatic relations between the United Arab Emirates, Bahrain, and Israel.

This has set in motion a domino effect, influencing Muslim majority Morocco and Sudan to break their embargoes on relations with the Jewish State.

For the first time, direct flights from Tel Aviv to popular destinations in Morocco will commence and Sudan has granted Israel overflight rights.

It must be said that the “Abraham Accords” built on the fertile grounds when in November 2018 Chadian President Idriss Deby visited Israel and established diplomatic relation two months later. Immediately thereafter, Mali started a diplomatic push to improve relations with Israel and apparently Mauretania could be next. Israel already has diplomatic relations with 42 out of the 44 Sub-Saharan states.

What promise would be underpinning the “Abraham Accords” offer Africa?

We have seen how America has coaxed Sudan to follow the process, by removing it from the list of terrorist-supporting states. One of the first Executive orders of Biden was to remove the ban on travel by many Muslim states to the US, and this will immediately affect several African countries. Biden will be more predisposed to follow his Democratic predecessors who displayed an acute desire to be involved with Africa, particularly to eradicate disease, improve food security and the quality of lives.

Attracting foreign investment is still the biggest need for African countries to build skills and create jobs and America can be expected to be more amenable to be accommodative. Despite China’s impressive growth, America still has the deepest pockets. Furthermore, China is being very assertive in spreading its influence in the South China Sea and across Asia with the “Silk Road” which removes its foot from the pedal with regards to Africa and creates a possible vacuum for the United States to fill. Moreover, African countries may be more open to American investment, particularly having experienced the onerous consequences of allowing unrestrained Chinese investment, which has resulted in debt and in economic exploitation.

With the Biden administration promising to re-engage with the world and re-build alliances, it will surely strengthen relations with its strongest ally in the Middle East, Israel.  Israel in turn has a tantalizing offering to address the most pressing problems faced by Africa, such as cleantech,cfood production and food security, sewage and sanitation treatments, andwater treatment.

Israeli Innovation

A recent report by the World Wide Fund for Nature lists Israel as the second most innovative country world-wide for clean technology, and the Global Cleantech 100 Index listed Israel as the world’s top innovator. With Global warming and the climate challenges, Cleantech is a necessary imperative to meet the Paris Agreement targets and covers the whole field of renewable energy technologies to make the world free from carbon emissions. Africa suffers from chronic power shortages and Cleantech will ensure that it is able to reach its economic growth targets in a sustainable way.

Israel’s prowess in desalination, where it operates the world’s largest desalination plants and has transformed itself from a water deficient country into an exporter of potable water, is well known. Less known is the fact that Israel recycles nearly 90 % of its sewage water for irrigation and industry making it a leader in the world. South Africa in comparison recycles less than 5 % and spews huge quantities of raw sewage into its rivers and seas. Israel treats sewage as a valuable commodity whereas in Africa it is a waste product that pollutes our water resources.

In agriculture, Israel has already built up a proud history of innovation in Africa such as making Kenya, Africa’s leading flower producer and introduced new varieties of vegetables, such as peppers and tomatoes and even seeds, such as the sesame. Israeli produced dripper lines are responsible for most of the food production in Africa and this is supported by Israeli agronomists, who have trained thousands of Africans and Israeli engineers planning, designing and building greenhouses.

In every field – from dairy production, where an Israeli company has taken control of Clover to satellite technology to facilitate communication – Israel can help Africa to leapfrog over its deficiencies in infrastructure and make up for its lack of development.

There is a time for everything, and this is the time to embrace the new paradigm that the “Abraham Accords” have unleashed for Israel’s new role in Africa.

Israeli Firm Providing Mobile Ventilators to California

ventilator corona

Agreement will make Inovytec’s lightweight Ventway Sparrow Turbine Ventilator available to Californians during and after Covid-19 pandemic.

By Abigail Klein Leichman, ISRAEL21c

Israeli medical device firm Inovytec has signed a deal to deliver 1,500 advanced portable ventilators to Global Medical Supply, a distributor that works with the state of California.

The Ventway Sparrow breathing machines will be used to aid patients with respiratory illnesses during the Covid-19 pandemic and beyond.

“When looking for a partner that could quickly supply us with the quality ventilators we needed, Inovytec answered the call. Its lightweight and durable ventilators give patients the flexibility needed to be transported between wards or hospitals seamlessly,” said Edward Kim, a partner at Global Medical Supply.

“At the same time, Inovytec’s ventilators are affordable, meaning we could care for more patients and the lack of constant maintenance allows us to keep them in storage if need be while knowing they will be ready when needed.”

The Ventway Sparrow weighs only 1 kilogram (2.2 pounds) and allows for invasive or noninvasive ventilation.

This ventilator is already being used in Covid-19 wards in Italy, Brazil and Israel. It is cleared for use in Canada, Australia and the United States under FDA Emergency Use Authorization.

Udi Kantor, cofounder and CEO of Inovytec, said ventilators have been an invaluable resource in recent months.

“Looking beyond the pandemic, our ventilators will enable paramedics and hospitals to safely and easily transfer patients, and we look forward to serving other medical facilities in California and other states.”

Inovytec also makes the Sali first-aid system for respiratory and cardiac emergencies; and the Lubo airway management and neck stabilization system for emergency medical teams. The company was founded in 2011.

Terrorist Attacks Soldiers Same Day Israel Offers Thousands of Vaccines to Palestinians

The IDF eliminated an Arab terrorist trying to stab to death soldiers on the same day the Israeli government announced it was transferring 5,000 corona vaccines to Palestinian medical workers.

By United with Israel Staff and AP

Palestinian terrorists who tried to stab to death Israeli soldiers on Sunday was fatally shot by troops on the scene.

“An armed assailant with three knives connected to a stick” attempted to attack soldiers at the Gush Etzion Junction south of Bethlehem, the army said in a statement.

No soldiers were hurt and the military confirmed the attacker was killed.

Video shared on social media shows a man in a grey sweatshirt walking along the side of a highway. He pulls something out of his clothes and begins to run toward a soldier. The soldier fires his weapon, and the man collapses.

The military shared a photo of the weapon, which appears to be a cluster of knives taped to a broom handle.

The terrorist mounted the attack on the same day Defense Minister Benny Gantz’s office announced announced Israel is giving 5,000 doses of the coronavirus vaccine to the Palestinians to immunize front-line medical workers.

Gantz’s office said early Sunday the transfer had been approved. There was no immediate comment from Palestinian officials.

Israel is one of the world’s leaders in vaccinating its population after striking procurement deals with international drug giants Pfizer and Moderna. The Health Ministry says nearly one-third of Israel’s 9.3 million people have received the first dose of the vaccine, while about 1.7 million people have received both doses.

The campaign includes Israel’s Arab citizens and Palestinians living in eastern portions of Jerusalem.

Palestinians living in Judea and Samaria are under the government of the Palestinian Authority, which is plagued by corruption and has refused to hold elections for over a decade.

Palestinians in Gaza are ruled by the Hamas terror group.

Despite Israel’s offer to assist the Palestinians with vaccine doses, Arab terrorists have mounted a series of shootings, stabbings and car-ramming attacks.

Last week, a Palestinian who attacked troops with a knife in northern Samaria. In December, a Palestinian murdered in cold blood Esther Horgan, an Israeli mother of six who was killed while she went jogging in the trails surrounding her community.

IDF eliminates terrorist committing stabbing attack in Gush Etzion